This is now primarily a pandemic of the unvaccinated and the mistrust of government and authority engrained in the American consciousness since the nation's inception has only fed into the problem. Low education and conspiracy theory driven portions of the population are going by rumor and feel and I don't think there is a solution for that. As a result, science-denying is now a growth industry.
It almost feels like a type of Darwinian natural selection which need not happen.
I used to think that people had evolved to some degree over the centuries but I know that to be absolutely untrue. While our technological tools have evolved, humans have remained largely the same.