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Androgen Insensitivity Syndrome

Androgen Insensitivity Syndrome (AIS) is a rare condition that affects a tiny portion of the population. It basically produces an individual that has the XY chromosomes of a genetic male but one who is either fully (CAIS) or partially (PAIS) insensitive to androgens which serve to masculinize the body at puberty. As a result AIS women do not have a uterus or fallopian tubes and cannot conceive children.

In the cases of full blown AIS (CAIS) the woman looks perfectly female albeit with a shallower than normal vagina, taller than average body proportions resulting in an almost Amazonian appearance in some cases. As a result some of the modeling and sports females have been accused of having AIS due to their exceptional height and above average beauty.

In the lower grades of PAIS the genitalia can be ambiguous and even produce a child that appears intersex or is more male than female.

AIS women do not menstruate which is why typically this condition is discovered at puberty. These young women typically go through a stigmatizing period where they must adapt to the reality that they are not conventional women and must adjust accordingly to their reality.

What is fascinating about this condition is that once again we see that nature does not correspond to the wills and wants of the doctrines that humankind has created. As a result anyone who does not fit the prescribed model of normalcy must hide for fear of persecution and prejudice. In the past and even today very few AIS women would publically admit to their condition and some have lost relationships upon disclosing this information.

It is also interesting to note is that a male to female transsexual that begins prepubescent treatment (via blockers for example) would be indistinguishable from an AIS woman from a genetic testing point of view as their body would also not have been subjected to androgens.


Eden Atwood (AIS woman) and her mother

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