This happened over a long period as the Republican party made major inroads into the midwest and the rural south where Democrats used to be in the majority. This contrast is so stark today that I am not sure there is a way to bridge the gap because it permeates all the way into the life mantra DNA.
Religious observance also separates the two groups which is something that does not endear one to the other. Perhaps this is what helps feed the anti-intellectual sentiment in the red states.
If there was ever a situation ripe for social unrest it is this one and, although it may not end in physical violence, in certain circles the resentment seems to border on it through being fed by fanning those internet echo chamber flames.